t-Butyl (8-amino-1,2,3,4-tetrahydro-3-quinolyl)carbamate → 5-(Dimethylamino)-5,6-dihydro-8-methoxy-4H-imidazo(4,5,1-ij)quinoline-2(1H)-one

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[C:11]([NH2:13])[CH:12]=1)[NH:9][CH2:8][CH:7]([N:14]([CH3:16])[CH3:15])[CH2:6]2.NC1C=CC=C2C=1NCC(N[C:29](=O)[O:30]C(C)(C)C)C2>>[CH3:16][N:14]([CH3:15])[CH:7]1[CH2:6][C:5]2[C:10]3=[C:11]([NH:13][C:29](=[O:30])[N:9]3[CH2:8]1)[CH:12]=[C:3]([O:2][CH3:1])[CH:4]=2

Participants

Reactant 2

HCID 19108500t-Butyl (8-amino-1,2,3,4-tetrahydro-3-quinolyl)carbamate

HCID 539614231,2,3,4-tetrahydro-6methoxy-N3,N3-dimethyl-3,8-quinolinediamine

Product 1

HCID 199193685-(Dimethylamino)-5,6-dihydro-8-methoxy-4H-imidazo(4,5,1-ij)quinoline-2(1H)-one

Procedure

This compound was prepared by following the procedure of Example 44 part B, but substituting, 1,2,3,4-tetrahydro-6methoxy-N3,N3 -dimethyl- 3,8-quinolinediamine for t-butyl (8-amino-1,2,3,4-tetrahydro-3-quinolyl)carbamate.

Workup

customThis compound was prepared

Sources & evidence

ORD record: ord-176be3b628754d08bbf9a8bec614910d
Source dataset: uspto-grants-1993_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05273975

Reaction notes

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