3-Chloro-2-butanone → 7-chloro-2-[(2-chloro-1-methylpropylidene) hydrazino]-5-phenyl-3H-1,4-benzodiazepine

HRID 328107

Reaction equation

HRID 328107 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1.[Cl:21][CH:22]([CH3:26])[C:23](=O)[CH3:24]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][N:13]=[C:23]([CH3:24])[CH:22]([Cl:21])[CH3:26])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1

Participants

3

Reactant 2

HCID 200263-Chloro-2-butanoneHCID 123908747-Chloro-2-hydrazinyl-5-phenyl-3H-1,4-benzodiazepine

Product 1

HCID 540115217-chloro-2-[(2-chloro-1-methylpropylidene) hydrazino]-5-phenyl-3H-1,4-benzodiazepine

Procedure

In the manner given in Example 1, 7-chloro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine can be reacted with 3-chloro-2-butanone to give 7-chloro-2-[(2-chloro-1-methylpropylidene) hydrazino]-5-phenyl-3H-1,4-benzodiazepine.

Sources & evidence

ORD record
ord-8f86aba3d62d480e8af066573caf737d
Source dataset
uspto-grants-1977_04
Patent number
US04016165

Linked notes

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