Palmitoyl chloride → N-methyl-N-(2-palmitoyloxyethyl)benzamide

HRID 328441

Reaction equation

[CH3:1][N:2]([CH2:11][CH2:12][OH:13])[C:3](=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[C:14](Cl)(=[O:30])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29]>>[CH3:1][N:2]([CH2:11][CH2:12][O:13][C:14](=[O:30])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[C:3](=[O:10])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

Reactant 2

HCID 8206Palmitoyl chloride

HCID 4047264N-(2-hydroxyethyl)-N-methylbenzamide

Product 1

HCID 21441878N-methyl-N-(2-palmitoyloxyethyl)benzamide

Procedure

N-methyl-N-(2-palmitoyloxyethyl)benzamide was prepared by the procedure of example 1 from 18 gms. (0.1 mole) of N-methyl-N-(2-hydroxyethyl)benzamide and 26 gms. (0.1 mole) of palmitoyl chloride. The structure of the final product was characterized on the basis of IR and NMR spectral analyses as described in example 1.

Workup

customN-methyl-N-(2-palmitoyloxyethyl)benzamide was prepared by the procedure of example 1 from 18 gms

Sources & evidence

ORD record: ord-a22d8476e6334d6093f69be5744eccf3
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04017522

Linked notes

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