Miconazole → 1-[2,4-Dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl]-3-(o-nitrobenzyl)imidazolium bromide

HRID 328635

Reaction equation

HRID 328635 reaction equation
[Cl:1][C:2]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:3]=1[CH:4]([O:11][CH2:12][C:13]1[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=1[Cl:20])[CH2:5][N:6]1[CH:10]=[CH:9][N:8]=[CH:7]1.[N+:26]([C:29]1[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=1[CH2:31][Br:32])([O-:28])=[O:27]>>[Br-:32].[Cl:1][C:2]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:3]=1[CH:4]([O:11][CH2:12][C:13]1[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=1[Cl:20])[CH2:5][N+:6]1[CH:10]=[CH:9][N:8]([CH2:31][C:30]2[CH:33]=[CH:34][CH:35]=[CH:36][C:29]=2[N+:26]([O-:28])=[O:27])[CH:7]=1

Participants

3

Reactant 2

HCID 4189MiconazoleHCID 77569alpha-Bromo-2-nitrotoluene

Product 1

HCID 1785265861-[2,4-Dichloro-beta-(2,4-dichlorobenzyloxy)phenethyl]-3-(o-nitrobenzyl)imidazolium bromide

Procedure

mp. 138.5° -141° C., by the reaction of 1-[2,4-dichloro-β-(2,4-dichlorobenzyloxy)phenethyl]-imidazole and o-nitrobenzyl bromide.

Sources & evidence

ORD record
ord-929fd014d85c4349b1144008cf694917
Source dataset
uspto-grants-1977_04
Patent number
US04017631

Linked notes

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