2-(4-Fluorophenyl)acetic acid → N-[2-(4-fluorophenyl)ethyl]cyclopropanamine

HRID 33048

Reaction equation

HRID 33048 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](O)=O)=[CH:4][CH:3]=1.[CH:12]1([NH2:15])[CH2:14][CH2:13]1>>[CH:12]1([NH:15][CH2:9][CH2:8][C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 98372-(4-Fluorophenyl)acetic acidHCID 69828Cyclopropylamine

Product 1

HCID 21098727N-[2-(4-fluorophenyl)ethyl]cyclopropanamine

Procedure

Synthesized according to typical procedures C and D from (4-fluorophenyl)acetic acid and cyclopropylamine.

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-94548278f4624a70b52248329b84a91f
Source dataset
uspto-grants-2008_09
Patent number
US07427613B2

Linked notes

Loading…