o-Tolylacetic acid → Cyclopropyl-(2-o-tolylethyl)amine
Reaction equation
[C:1]1([CH3:11])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][C:8](O)=O.[CH:12]1([NH2:15])[CH2:14][CH2:13]1>>[CH:12]1([NH:15][CH2:8][CH2:7][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=2[CH3:11])[CH2:14][CH2:13]1Participants
3
Procedure
Synthesized according to typical procedures C and D from o-tolylacetic acid and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-22aefdeba39b42d4acf7379e54ec7b64
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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