Cyclopropylamine → (2-Chloro-3-trifluoromethyl-benzyl)-cyclopropyl-amine
Reaction equation
[Cl:1][C:2]1[C:9]([C:10]([F:13])([F:12])[F:11])=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[CH:14]1([NH2:17])[CH2:16][CH2:15]1>>[Cl:1][C:2]1[C:9]([C:10]([F:13])([F:12])[F:11])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH:17][CH:14]1[CH2:16][CH2:15]1Participants
3
Procedure
Synthesized according to typical procedure J from 2-chloro-3-trifluoromethylbenzaldehyde and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-2b94c71f620c4316a3431a353cc8bdf2
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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