Cyclopropylamine → Cyclopropyl-(5-fluoro-2-methoxybenzyl)amine
Reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:10][CH3:11])=[C:6]([CH:9]=1)[CH:7]=O.[CH:12]1([NH2:15])[CH2:14][CH2:13]1>>[CH:12]1([NH:15][CH2:7][C:6]2[CH:9]=[C:2]([F:1])[CH:3]=[CH:4][C:5]=2[O:10][CH3:11])[CH2:14][CH2:13]1Participants
3
Procedure
Synthesized according to typical procedure J from 5-fluoro-2-methoxybenzaldehyde and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-501e2acf0e04436e8221777de2d256ee
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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