Cyclopropylamine → N-(3,5-difluorobenzyl)cyclopropanamine
Reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([F:10])[CH:9]=1)[CH:5]=O.[CH:11]1([NH2:14])[CH2:13][CH2:12]1>>[CH:11]1([NH:14][CH2:5][C:4]2[CH:3]=[C:2]([F:1])[CH:9]=[C:8]([F:10])[CH:7]=2)[CH2:13][CH2:12]1Participants
3
Procedure
Synthesized according to typical procedure J from 3,5difluorobenzaldehyde and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-290bb215c6b0405b91b232647b89c048
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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