Cyclopropylamine → N-[(2,3-difluorophenyl)methyl]cyclopropanamine
Reaction equation
[F:1][C:2]1[C:9]([F:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[CH:11]1([NH2:14])[CH2:13][CH2:12]1>>[CH:11]1([NH:14][CH2:4][C:3]2[CH:6]=[CH:7][CH:8]=[C:9]([F:10])[C:2]=2[F:1])[CH2:13][CH2:12]1Participants
3
Procedure
Synthesized according to typical procedure J from 2,3-difluorobenzaldehyde and cyclopropylamine.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-f9b952e5136941b290317a99cd97073a
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07427613B2
Reaction notes
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