Bromine → 2-Bromoindenone

HRID 331258

Reaction equation

HRID 331258 reaction equation
[C:1]1(=[O:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[Br:11]Br>C(Cl)Cl>[Br:11][C:2]1[C:1](=[O:10])[C:9]2[C:4]([CH:3]=1)=[CH:5][CH:6]=[CH:7][CH:8]=2

Participants

4

Reactant 2

HCID 24408BromineHCID 118153841H-inden-1-one

Product 1

HCID 99906492-Bromoindenone

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The indenone of formula 23 prepared in Step 2 is dissolved in CH2Cl2, 1M Br2 solution (dissolved in CH2Cl2) is added thereto. The resulting mixture is stirred for 2 to 3 h at room temperature, to obtain the 2-bromoindenone of formula 17.

Sources & evidence

ORD record
ord-16453f5f62194f7e87fa552a871847dd
Source dataset
uspto-grants-2014_11
Patent number
US08877747B2

Linked notes

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