2-Amino-4-chlorobenzenethiol → US9663460, Example 14

HRID 332198

Reaction equation

HRID 332198 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[SH:9].[CH:10]([NH:13][C:14](=[O:17])[CH:15]=[CH2:16])([CH3:12])[CH3:11].[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([S:25](Cl)(=[O:27])=[O:26])=[CH:21][C:20]=1[C:29]([F:32])([F:31])[F:30]>>[Cl:8][C:6]1[CH:5]=[CH:4][C:3]([S:9][CH2:16][CH2:15][C:14]([NH:13][CH:10]([CH3:12])[CH3:11])=[O:17])=[C:2]([NH:1][S:25]([C:22]2[CH:23]=[CH:24][C:19]([Cl:18])=[C:20]([C:29]([F:32])([F:30])[F:31])[CH:21]=2)(=[O:27])=[O:26])[CH:7]=1

Participants

4

Reactant 3

HCID 120002-Amino-4-chlorobenzenethiolHCID 16637N-IsopropylacrylamideHCID 27807194-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride

Product 1

HCID 57378422US9663460, Example 14

Procedure

Following General Procedure H, B, the title compound was prepared from 2-amino-4-chloro-benzenethiol, N-isopropyl-acrylamide, and 4-chloro-3-trifluoromethyl-benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-855e65473a61449cb52eabb6d3290f82
Source dataset
uspto-grants-2014_11
Patent number
US08877804B2

Linked notes

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