Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 4-(4-Nitrophenyl)morpholine | HCID 25222 | — |
Reaction Steps
A mixture of 24.5 g morpholine and 13.3 g 1-Fluoro-4-nitro-benzene in 30 ml DMSO was heated to 100° C. for 4 h. This solution was poured on to 300 ml of water and the resulting precipitate was collected by filtration to yield a bright yellow crystalline product, which was dried in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07429581B2 |
|---|
| Source dataset | uspto-grants-2008_09 |
|---|
| ORD ID | ord-c1072cb05350480f9b5edd1aa57fc23c |
|---|
| Source note | uspto-grants-2008_09 |
|---|
