HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-(1-methylethylidene)hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Propanone, methylhydrazone | HCID 79840 | — |
| Reactant | 2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl chloride | HCID 56942712 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-[2-(2,6-Diethyl-4-methylphenyl)-2-oxoacetyl]-1-methyl-2-(1-methylethylidene)hydrazine | HCID 86689343 | — |
Reaction Conditions
| Temperature | 1 °C |
|---|
Reaction Steps
To a 1000 ml volume four-necked flask, 1-methyl-2-(2-propylidene)hydrazine (17-a) (9.61 g), acetonitrile (280 ml), and triethylamine (17 ml) were added under a nitrogen atmosphere and cooled to about 1° C. To the mixture, 2-(2,6-diethyl-4-methylphenyl)-2-oxoacetyl chloride (6-a) (27.12 g) dissolved in acetonitrile (77 ml) was added dropwise over 30 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08884010B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-32796de4843940589233da3d6cd68bbe |
| Source note | uspto-grants-2014_11 |