HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Thioglycolate → 5,7-Difluoro-benzo[B]thiophene-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Thioglycolate | HCID 16907 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2,3,5-Trifluorobenzaldehyde | HCID 2776950 | — |
| Product | 5,7-Difluoro-benzo[B]thiophene-2-carboxylic acid methyl ester | HCID 57350890 | — |
Reaction Steps
Using 3.94 g (24.6 mmol) of 2,3,5-trifluorobenzaldehyde, 1.48 g (36.9 mmol) of sodium hydride (60% pure) and 2.88 g (27.1 mmol) of methyl mercaptoacetate,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08884017B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-97fd5168b01b4cc6823644167562b3ef |
| Source note | uspto-grants-2014_11 |