(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid → (R)-2-Amino-3-(4-methoxy-benzylsulfanyl)propionic acid methyl ester

HRID 336450Notes

Reaction equation

HRID 336450 reaction equation
[C:1]([C@@:8]([NH2:23])([CH2:12][S:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)C(O)=O)([O:3][C:4](C)(C)C)=[O:2]>CO>[CH3:4][O:3][C:1](=[O:2])[C@@H:8]([NH2:23])[CH2:12][S:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1

Participants

3

Reactant 1

HCID 68486000(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid

Product 1

HCID 14390800(R)-2-Amino-3-(4-methoxy-benzylsulfanyl)propionic acid methyl ester

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid prepared in Step B of Preparation 27 and methanol were reacted according to the same procedure as

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-e0d3c876ccfb4d54a4a259a0042287a9
Source dataset
uspto-grants-2014_11
Patent number
US08889691B2

Reaction notes

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