ER-35786 → 3,5-Dimethyl-1-hexyn-3-ol

Reaction equation

C(O)#C[OH:3].[CH3:5][C@H:6]1[C:13](S[C@@H]2CN[C@H]([C@H](O)[C@H]3CNCC3)C2)=C(C(O)=O)N2[C@H:7]1[C@@H:8]([C@H:30](O)[CH3:31])[C:9]2=O.Cl>>[CH3:5][CH:6]([CH2:7][C:8]([OH:3])([C:30]#[CH:31])[CH3:9])[CH3:13]

Participants

Reactant 2

HCID 6918311ER-35786

HCID 9942115Acetylene glycol

Product 1

HCID 610183,5-Dimethyl-1-hexyn-3-ol

Procedure

For example, any commercially available product may be used for the acetylene diol compound. The commercially available product includes, for example, “Olfin (trade name) E1010” and “Olfin (trade name) E1004” as well as “Surfynol (trade name) 440” and “Surfynol (trade name) 465” produced by Nissin Chemical Industry Co., Ltd.; and “Acetylenol (trade name) E40” and “Acetylenol (trade name) E100” produced by Kawaken Fine Chemicals Co., Ltd.

Sources & evidence

ORD record: ord-4e67c40a803348bcaecdf2d7b276d516
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08889762B2

Reaction notes

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