(1S*,2R*)-2-(1-Ethyl-1H-pyrazol-5-yl)cyclopentanol → HCID 89962477, compound

HRID 337919

Reaction equation

HRID 337919 reaction equation
[CH2:1]([N:3]1[C:7]([C@H:8]2[CH2:12][CH2:11][CH2:10][C@@H:9]2[OH:13])=[CH:6][CH:5]=[N:4]1)[CH3:2]>CCCCCC.C(O)C>[CH2:1]([N:3]1[C:7]([C@@H:8]2[CH2:12][CH2:11][CH2:10][C@H:9]2[OH:13])=[CH:6][CH:5]=[N:4]1)[CH3:2]

Participants

3

Reactant 1

HCID 89962858(1S*,2R*)-2-(1-Ethyl-1H-pyrazol-5-yl)cyclopentanol

Product 1

HCID 89962477HCID 89962477, compound

Reagents, catalysts & solvents 1

HCID 21879635Ethanol hexaneSolvent

Procedure

The (1S*,2R*)-2-(1-ethyl-1H-pyrazol-5-yl)cyclopentanol prepared in Example 37a was optically resolved with CHIRALPAK AD-H (Daicel Corp.; hexane/ethanol=8:2) to yield the title compound as a colorless oil.

Sources & evidence

ORD record
ord-4f23d62afb48461dbab7291e5b9b4d86
Source dataset
uspto-grants-2014_11
Patent number
US08889741B2

Linked notes

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