HCID 89962282, compound → HCID 89962478, compound
Reaction equation
[NH:1]1[CH:5]=[C:4]([C@@H:6]2[CH2:11][CH2:10][CH2:9][CH2:8][C@H:7]2[OH:12])[CH:3]=[N:2]1>CCCCCC.C(O)C>[NH:1]1[CH:5]=[C:4]([C@H:6]2[CH2:11][CH2:10][CH2:9][CH2:8][C@@H:7]2[OH:12])[CH:3]=[N:2]1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The (1R*,2S*)-2-(1H-pyrazol-4-yl)cyclohexanol prepared in Example 169a was optically resolved with CHIRALPAK AD-H (Daicel Corp.; hexane/ethanol=8:2) to yield the title compound as a colorless solid.
Sources & evidence
- ORD record
- ord-ab7cde65aab04395ba9643091c101d2b
- Source dataset
- uspto-grants-2014_11
- Patent number
- US08889741B2
Reaction notes
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