Formic Acid → HCID 178420610, compound
Reaction equation
[N:1]1[C:6](C=O)=[CH:5][CH:4]=[CH:3][C:2]=1C=O.[NH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(O)=O>C(O)C>[C:12]1([N:11]=[C:6]2[CH2:5][CH:4]=[CH:3][C:2](=[N:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[NH:1]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
2,6-pyridine dicarboxaldehyde (0.3071 g, 2.3 mmol) was added to a solution of aniline (0.5292 g, 5.7 mmol) in absolute ethanol (20 mL) at room temperature. 0.5 mL of formic acid was then added to the above solution. The mixture was stirred at room temperature for 65 hours. The product was filtered, washed with cold ethanol and dried in a vacuum oven (50° C.) overnight. Yield 0.2245 g (34.2%).
Workup
- filtrationThe product was filtered
- washwashed with cold ethanol
- customdried in a vacuum oven (50° C.) overnight
Sources & evidence
- ORD record
- ord-21efaacccac443d7a83aa3e70255ab54
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07429684B2
Reaction notes
Loading…