Formic Acid → HCID 178420610, compound

HRID 33818

Reaction equation

HRID 33818 reaction equation
[N:1]1[C:6](C=O)=[CH:5][CH:4]=[CH:3][C:2]=1C=O.[NH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(O)=O>C(O)C>[C:12]1([N:11]=[C:6]2[CH2:5][CH:4]=[CH:3][C:2](=[N:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[NH:1]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 284Formic AcidHCID 6115AnilineHCID 794852,6-Diformylpyridine

Product 1

HCID 178420610HCID 178420610, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2,6-pyridine dicarboxaldehyde (0.3071 g, 2.3 mmol) was added to a solution of aniline (0.5292 g, 5.7 mmol) in absolute ethanol (20 mL) at room temperature. 0.5 mL of formic acid was then added to the above solution. The mixture was stirred at room temperature for 65 hours. The product was filtered, washed with cold ethanol and dried in a vacuum oven (50° C.) overnight. Yield 0.2245 g (34.2%).

Workup

  1. filtrationThe product was filtered
  2. washwashed with cold ethanol
  3. customdried in a vacuum oven (50° C.) overnight

Sources & evidence

ORD record
ord-21efaacccac443d7a83aa3e70255ab54
Source dataset
uspto-grants-2008_09
Patent number
US07429684B2

Linked notes

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