2-Amino-4-(trifluoromethyl)benzenethiol → HCID 68279297, compound

HRID 338799

Reaction equation

HRID 338799 reaction equation
C([CH2:3][C:4]([O:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]=O)=[CH:12][CH:11]=1)([CH3:8])[C:5]([OH:7])=[O:6])C.[NH2:18][C:19]1[CH:24]=[C:23]([C:25]([F:28])([F:27])[F:26])[CH:22]=[CH:21][C:20]=1[SH:29]>CO>[CH3:8][C:4]([O:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]2[S:29][C:20]3[CH:21]=[CH:22][C:23]([C:25]([F:26])([F:27])[F:28])=[CH:24][C:19]=3[N:18]=2)=[CH:14][CH:15]=1)([CH3:3])[C:5]([OH:7])=[O:6]

Participants

4

Reactant 2

HCID 880422-Amino-4-(trifluoromethyl)benzenethiolHCID 86709921HCID 86709921, compound

Product 1

HCID 68279297HCID 68279297, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution including Compound 97c (1.0 eq.) and 2-amino-4-trifluoromethylbenzenethiol (1.0 eq.) was stirred in a methanol solvent at room temperature. After methanol was removed, the precipitate was filtered, and washed with cold methanol to obtain a solid target product.

Workup

  1. customAfter methanol was removed
  2. filtrationthe precipitate was filtered
  3. washwashed with cold methanol
  4. customto obtain a solid target product

Sources & evidence

ORD record
ord-b82717d95259479bb2385f249cfa8728
Source dataset
uspto-grants-2014_11
Patent number
US08889881B2

Linked notes

Loading…