4-(quinolin-2-ylmethoxy)benzoic Acid → 4-(Benzyloxy)-2-fluorobenzoic acid

HRID 33896

Reaction equation

HRID 33896 reaction equation
N1C2C(=CC=CC=2)C=CC=1COC1C=CC(C(O)=O)=CC=1.C([O:29][C:30](=[O:46])[C:31]1[CH:36]=[CH:35][C:34]([O:37][CH2:38][C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)=[CH:33][C:32]=1[F:45])C1C=CC=CC=1>>[CH2:38]([O:37][C:34]1[CH:35]=[CH:36][C:31]([C:30]([OH:46])=[O:29])=[C:32]([F:45])[CH:33]=1)[C:39]1[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1

Participants

3

Reactant 2

HCID 98385524-(quinolin-2-ylmethoxy)benzoic AcidHCID 57916590Benzyl 4-benzyloxy-2-fluorobenzoate

Product 1

HCID 223145024-(Benzyloxy)-2-fluorobenzoic acid

Procedure

Following the procedure for the preparation of 4-(Quinolin-2-ylmethoxy)-benzoic acid but substituting 4-Benzyloxy-2-fluoro-benzoic acid benzyl ester provided the title compound. MS: (M+H m/z=247.1).

Sources & evidence

ORD record
ord-132db728347c417ead9af68b6e69d5ef
Source dataset
uspto-grants-2008_09
Patent number
US07429665B2

Linked notes

Loading…