Quinoline → 2-Chloro-N-cyclopropyl-4-[(1Z)-3-oxo-3-({2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]ethyl}-amino)prop-1-en-1-yl]benzamide
Reaction equation
[Cl:1][C:2]1[CH:13]=[C:12]([C:14]#[C:15][C:16](=[O:33])[NH:17][CH:18]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([C:29]([F:32])([F:31])[F:30])[CH:24]=2)[C:19]([F:22])([F:21])[F:20])[CH:11]=[CH:10][C:3]=1[C:4]([NH:6][CH:7]1[CH2:9][CH2:8]1)=[O:5].N1C2C(=CC=CC=2)C=CC=1>CO.[Pd]>[Cl:1][C:2]1[CH:13]=[C:12](/[CH:14]=[CH:15]\[C:16](=[O:33])[NH:17][CH:18]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([C:29]([F:30])([F:31])[F:32])[CH:24]=2)[C:19]([F:22])([F:20])[F:21])[CH:11]=[CH:10][C:3]=1[C:4]([NH:6][CH:7]1[CH2:8][CH2:9]1)=[O:5]Participants
5
