3,4-Dimethylbenzoic acid → 3,4-dimethyl-N-(5-methylhexan-3-yl)benzamide

HRID 339360

Reaction equation

HRID 339360 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([OH:7])=O.[CH3:12][CH:13]([CH3:19])[CH2:14][CH:15]([NH2:18])[CH2:16][CH3:17]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([NH:18][CH:15]([CH2:14][CH:13]([CH3:19])[CH3:12])[CH2:16][CH3:17])=[O:7]

Participants

3

Reactant 2

HCID 120733,4-Dimethylbenzoic acidHCID 229554965-Methylhexan-3-amine

Product 1

HCID 575279023,4-dimethyl-N-(5-methylhexan-3-yl)benzamide

Procedure

Prepared in a similar manner to example 4 using 3,4-dimethylbenzoic acid and 5-methylhexan-3-amine (example 5a). 1H NMR (500 MHz, CDCl3): δ 0.94 (m, 9H); 1.38 (m, 2H); 1.46 (m, 1H); 1.65 (m, 2H); 2.29 (s, 3H); 2.30 (s, 3H); 4.18 (m, 1H); 5.70 (d, 1H); 7.17 (d, 1H); 7.46 (d, 1H); 7.55 (s, 1H). MS (248, M+H).

Sources & evidence

ORD record
ord-6faf48d13fac4097bd7a4dd7022f8c19
Source dataset
uspto-grants-2014_11
Patent number
US08895050B2

Linked notes

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