4-Methoxy cinnamic acid → N-(1-Benzyl-2-hydroxy-ethyl)-3-(4-methoxy-phenyl)-acrylamide

HRID 339369

Reaction equation

HRID 339369 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([OH:13])=O)=[CH:5][CH:4]=1.[NH2:14][C@@H:15]([CH2:23][OH:24])[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([CH:15]([NH:14][C:11](=[O:13])[CH:10]=[CH:9][C:6]1[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=1)[CH2:23][OH:24])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 132454-Methoxy cinnamic acidHCID 853475phenylalaninol, (R)-

Product 1

HCID 66775404N-(1-Benzyl-2-hydroxy-ethyl)-3-(4-methoxy-phenyl)-acrylamide

Procedure

Prepared in a similar manner as described in example 4 from 3-(4-methoxy-phenyl)-acrylic acid and D-phenylalaninol. MS (M+H, 312.3).

Workup

  1. customPrepared in a similar manner

Sources & evidence

ORD record
ord-d7ca3a167f834262bb93fcf1a3734879
Source dataset
uspto-grants-2014_11
Patent number
US08895050B2

Linked notes

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