Water → 2-(4-formylphenyl)acetic Acid
Reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1.[OH2:13]>>[CH:2]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1)=[O:13]Participants
3
Procedure
[4-(Bromomethyl)phenyl]acetic acid (4.6 g) and cupric nitrate trihydrate (5 g) were suspended in water (50 mL) and heated at reflux for 1 hr. The solution was allowed to cool and the resulting white solid collected and washed with water to give the subtitle compound (2.06 g); MS multimode (+) 165
Workup
- temperatureheated
- temperatureat reflux for 1 hr
- temperatureto cool
- customthe resulting white solid collected
- washwashed with water
Sources & evidence
- ORD record
- ord-dde3cd1bc1064f949e894277c065fe41
- Source dataset
- uspto-grants-2014_11
- Patent number
- US08895570B2
Reaction notes
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