N,N,2,2-Tetramethylpropane-1,3-diamine → 6-Arylpyrido[2,3-d]pyrimidine deriv. 40

HRID 3422

Reaction equation

HRID 3422 reaction equation
[NH2:1][C:2]1[N:3]=[CH:4][C:5]2[CH:11]=[C:10]([C:12]3[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=3[Cl:19])[C:9]([NH2:20])=[N:8][C:6]=2[N:7]=1.[CH3:21][N:22]([CH3:29])[CH2:23][C:24]([CH3:28])([CH3:27])[CH2:25]N>>[NH2:20][C:9]1[C:10]([C:12]2[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:19])=[CH:11][C:5]2[CH:4]=[N:3][C:2]([NH:1][CH2:25][C:24]([CH3:28])([CH3:27])[CH2:23][N:22]([CH3:29])[CH3:21])=[N:7][C:6]=2[N:8]=1

Participants

3

Reactant 2

HCID 104477N,N,2,2-Tetramethylpropane-1,3-diamineHCID 53281136-(2,6-Dichlorophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine

Product 1

HCID 53281426-Arylpyrido[2,3-d]pyrimidine deriv. 40

Procedure

The title compound was prepared as described above in Example 20 by reacting 2.0 g of 2,7-diamino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidine from Example 1 and 15 mL of N,N,2,2-tetramethyl-1,3-propanediamine.

Sources & evidence

ORD record
ord-6e213f658a414f92bb126f7532f74911
Source dataset
uspto-grants-1998_03
Patent number
US05733913

Linked notes

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