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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34352Generated: October 26, 2026

Benzodiazepine → 9-Methylthio-6-(4-methyl-1-piperazinyl)1,2-dihydrobenzo[b]pyrrolo(3,2,1-jk][1,4]benzodiazepine

https://huagongshe.com/reaction/34352

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzodiazepineHCID 134664—
ReactantN-[5-methylthio-2-(2,3-dihydro-1H-indol-1-yl)phenyl]-4-methyl-1-piperazinecarboxamideHCID 21297642—
Product9-Methylthio-6-(4-methyl-1-piperazinyl)1,2-dihydrobenzo[b]pyrrolo(3,2,1-jk][1,4]benzodiazepineHCID 21297643—

Reaction Steps

It is predicted that if the N-[5-methylthio-2-(2,3-dihydro-1H-indol-1-yl)phenyl]-4-methyl-1-piperazinecarboxamide of Example 10c is treated in the manner of Example 4c that 9-methylthio-6-(4-methyl-1-piperazinyl)-1,2-dihydrobenzo[b]pyrrolo[3,2,1-jk]-1,4]benzodiazepine will be obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04761412
Source datasetuspto-grants-1988_08
ORD IDord-ddb6f947abfe4960a293ee423c4a3354
Source noteuspto-grants-1988_08