Water → 7,12-Dioxaspiro(5,6)dodec-9-ene
Reaction equation
[CH3:1]/[CH:2]=[CH:3]\[CH3:4].[C:5]1(=[O:11])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1.[OH2:12]>C1C=CC=CC=1>[CH2:10]1[C:5]2([O:12][CH2:4][CH:3]=[CH:2][CH2:1][O:11]2)[CH2:6][CH2:7][CH2:8][CH2:9]1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Cis-but-2-ene, 4-diol (50 g), cyclohexanone (50 g) and SNCA catalyst (2.5 g) were refluxed in benzene (75 ml) using a Deanstark water separator. The catalyst was filtered, the solvent evaporated and the residue distilled at 80°-85° C./4 torr to give 7,12-dioxaspiro[5,6]dodec-9-ene of formula III (92%) of the drawings.
Workup
- filtrationThe catalyst was filtered
- customthe solvent evaporated
- distillationthe residue distilled at 80°-85° C./4 torr
Sources & evidence
- ORD record
- ord-8cf90097f01d4ebfb31858726b31caf2
- Source dataset
- uspto-grants-1999_01
- Patent number
- US05864046
Reaction notes
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