Calcium Carbonate → 3-(1-Hydroxyethyl)benzophenone

HRID 34472

Reaction equation

HRID 34472 reaction equation
C(=O)([O-])[O-:2].[Ca+2].Br[CH:7]([C:9]1[CH:10]=[C:11]([CH:20]=[CH:21][CH:22]=1)[C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:13])[CH3:8]>O>[OH:2][CH:7]([C:9]1[CH:10]=[C:11]([CH:20]=[CH:21][CH:22]=1)[C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:13])[CH3:8]

Participants

4

Reactant 2

HCID 10112Calcium CarbonateHCID 128029243-(1-Bromoethyl)benzophenone

Product 1

HCID 131027513-(1-Hydroxyethyl)benzophenone

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
120 °C

Procedure

In an autoclave, 100 ml of water and 3.3 g of calcium carbonate and 10 g of 3-(1-bromoethyl)benzophenone were placed, and were then heated at 120° C. for 6 hours. The resultant reaction solution was extracted with benzene, and a formed benzene layer was then dried with anhydrous sodium sulfate, followed by distilling off the solvent. The resultant product had the spectrum data which were identical with those of 3-(1-hydroxyethyl)benzophenone.

Workup

  1. customThe resultant reaction solution
  2. extractionwas extracted with benzene
  3. dry with materiala formed benzene layer was then dried with anhydrous sodium sulfate
  4. distillationby distilling off the solvent

Sources & evidence

ORD record
ord-fc7d2b8db3824fb2971244479323f773
Source dataset
uspto-grants-1988_08
Patent number
US04761508

Linked notes

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