HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → 2-Methoxynaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | 1-(6-Methoxy-2-naphthalenyl)-1-propanone | HCID 75913 | — |
| Reactant | 1-(5-Bromo-6-methoxy-2-naphthyl)-1-propanone | HCID 1471998 | — |
| Product | 2-Methoxynaphthalene | HCID 7119 | — |
| Product | 1-Bromo-2-methoxynaphthalene | HCID 72860 | — |
Reaction Steps
Compared with the preparation of analogues of the compound II-A, ie 1-(6-methoxy-2-naphthyl)-1-propanone (II, X=H) and 1-(5-bromo-6-methoxy-2-naphthyl)-1-propanone (II, X=Br) by a Friedel-Crafts reaction between propionyl chloride and, respectively, 2-methoxy-naphthalene and 1-bromo-2-methoxy-naphthalene, the following advantages are obtained:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05053533 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-cea67d77e28d4f65a55a0bdda9b98b9c |
| Source note | uspto-grants-1991_10 |