Benzeneacetonitrile, 2,3,6-trichloro- → 6-(2,3,6-Trichloro-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

HRID 3457

Reaction equation

HRID 3457 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[C:4]([Cl:9])[C:3]=1[CH2:10][C:11]#[N:12].[NH2:13][C:14]1[N:19]=[C:18]([NH2:20])[C:17]([CH:21]=O)=[CH:16][N:15]=1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[C:4]([Cl:9])[C:3]=1[C:10]1[C:11]([NH2:12])=[N:20][C:18]2[N:19]=[C:14]([NH2:13])[N:15]=[CH:16][C:17]=2[CH:21]=1

Participants

3

Reactant 2

HCID 76679Benzeneacetonitrile, 2,3,6-trichloro-HCID 3091762,4-Diaminopyrimidine-5-carbaldehyde

Product 1

HCID 218500306-(2,3,6-Trichloro-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

Procedure

The title compound was prepared according to Example 1, starting from 1.0 g of (2,3,6-trichloro)-phenyl-acetonitrile and 0.6 g of 2,4-diamino-5-pyrimidine-carboxaldehyde; mp 320°-322° C.

Sources & evidence

ORD record
ord-bf51f18e6d724e79a90be7ff7f0aee82
Source dataset
uspto-grants-1998_03
Patent number
US05733913

Linked notes

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