Barium hydroxide → Thiomandelic acid

HRID 346245

Reaction equation

HRID 346245 reaction equation
[C:1]1([CH:7]2[S:11]C(=N)N[C:8]2=[O:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-:14].[Ba+2].[OH-]>C(O)C>[SH:11][CH:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[C:8]([OH:13])=[O:14]

Participants

4

Reactant 2

HCID 6093286Barium hydroxideHCID 1356332132-Amino-5-phenyl-1,3-thiazol-4-one

Product 1

HCID 10464709Thiomandelic acidYield 70%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Hydrolysis of 142 g of 5-phenyl-2-imino-4-thiazolidinone with barium hydroxide in 20% aqueous ethanol gave 55 g of α-mercaptophenylacetic acid (70% yield).

Sources & evidence

ORD record
ord-acdc8c1a458d4119a821fc56cfb443ee
Source dataset
uspto-grants-1991_10
Patent number
US05061720

Linked notes

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