Acetone → 4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane

HRID 34692

Reaction equation

HRID 34692 reaction equation
[Br:1][CH2:2][CH:3]([OH:6])[CH2:4][OH:5].S([O-])([O-])(=O)=O.[Mg+2].[CH3:13][C:14]([CH3:16])=O>>[CH3:13][C:14]1([CH3:16])[O:6][CH:3]([CH2:2][Br:1])[CH2:4][O:5]1

Participants

4

Reactant 3

HCID 180AcetoneHCID 208273-Bromo-1,2-propanediolHCID 24083Sulfuric acid magnesium salt (1:1)

Product 1

HCID 1697594-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane

Procedure

An acetone solution of bromomethyl ethylene glycol is refluxed for 24 hours in the presence of anhydrous magnesium sulfate. The cooled reaction mixture is filtered and the solvent is removed to provide a residual crude product.

Workup

  1. customThe cooled reaction mixture
  2. filtrationis filtered
  3. customthe solvent is removed

Sources & evidence

ORD record
ord-01f407b26c404daab6db59143a8e4364
Source dataset
uspto-grants-1988_08
Patent number
US04762912

Linked notes

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