(3-Methoxyphenyl)acetonitrile → 6-(3-Methoxy-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

HRID 3473

Reaction equation

HRID 3473 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[CH2:6][C:7]#[N:8].[NH2:12][C:13]1[N:18]=[C:17]([NH2:19])[C:16]([CH:20]=O)=[CH:15][N:14]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:6]2[C:7]([NH2:8])=[N:19][C:17]3[N:18]=[C:13]([NH2:12])[N:14]=[CH:15][C:16]=3[CH:20]=2)[CH:9]=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 88310(3-Methoxyphenyl)acetonitrileHCID 3091762,4-Diaminopyrimidine-5-carbaldehyde

Product 1

HCID 218500446-(3-Methoxy-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

Procedure

The title compound was prepared according to Example 1, starting from 3-methoxybenzyl cyanide and 2,4-diamino-5-pyrimidine-carboxaldehyde; mp 284°-286 ° C.

Sources & evidence

ORD record
ord-fa8564de9b1f4376bd8bb985447ab6eb
Source dataset
uspto-grants-1998_03
Patent number
US05733913

Linked notes

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