Putrescine → HCID 178512945, compound

HRID 34748

Reaction equation

HRID 34748 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][NH2:6].CS[C:9](=[NH:11])[NH2:10].OS(O)(=O)=O>O>[NH:1]([CH2:2][CH2:3][CH2:4][CH2:5][NH2:6])[C:9]([NH2:11])=[NH:10]

Participants

5

Reactant 3

HCID 1045PutrescineHCID 1118Sulfuric AcidHCID 51422-Methyl-2-thiopseudourea

Product 1

HCID 178512945HCID 178512945, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent3×

Procedure

To 1.8 g. of 1,4-diaminobutane dissolved in 50 ml. of H2O was added, dropwise, a solution of 2 g. of S-methylthiopseudourea.H2SO4 in 20 ml. of H2O. Throughout the addition, the solution was stirred vigorously and continued for 12 hours after the completion of addition. Then H2O was lyophilized, giving viscous colorless oil, which upon addition of 50 ml. of methanol precipitated 1.05 g. of white powder. Mass spec. (FD.) ions at m/e 228 and 130 for H2N--(CH2)4 --NHC(=NH)--NH2.H2O4 and H2N--(CH2)4 --NHC(=NH)--NH2, respectively.

Workup

  1. additionThroughout the addition
  2. additionafter the completion of addition
  3. customgiving viscous colorless oil, which
  4. additionupon addition of 50 ml
  5. customof methanol precipitated 1.05 g

Sources & evidence

ORD record
ord-2f570d8df0f44c80ad9a8640ae3b2dba
Source dataset
uspto-grants-1988_08
Patent number
US04762949

Linked notes

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