Thionyl Chloride → 5-Bromofuran-2-carbonyl chloride
Reaction equation
[Br:1][C:2]1[O:6][C:5]([C:7]([OH:9])=O)=[CH:4][CH:3]=1.S(Cl)([Cl:12])=O>C1(C)C=CC=CC=1>[Br:1][C:2]1[O:6][C:5]([C:7]([Cl:12])=[O:9])=[CH:4][CH:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
21.0 g of 5-bromo-2-furancarboxylic acid were suspended in 650 ml of toluene and 40 ml of thionyl chloride and the suspension was heated to reflux for 2 hours. The reaction solution was thereafter concentrated, whereby 5-bromo-2-furancarboxylic acid chloride was obtained as the residue.
Workup
- temperatureto reflux for 2 hours
- concentrationThe reaction solution was thereafter concentrated
Sources & evidence
- ORD record
- ord-374bfbb4f33346df9af44276ccb38c16
- Source dataset
- uspto-grants-1988_08
- Patent number
- US04764522
Reaction notes
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