5-Hydrazinyl-2-methoxypyridine dihydrochloride → HCID 21091009, compound

Reaction equation

[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[CH:12][C:13]#[N:14])=[CH:7][CH:6]=1.Cl.Cl.[CH3:17][O:18][C:19]1[CH:24]=[CH:23][C:22]([NH:25][NH2:26])=[CH:21][N:20]=1>>[CH3:1][O:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]2[N:25]([C:22]3[CH:21]=[N:20][C:19]([O:18][CH3:17])=[CH:24][CH:23]=3)[N:26]=[C:13]([NH2:14])[CH2:12]2)=[CH:7][CH:6]=1

Participants

Reactant 2

HCID 223415725-Hydrazinyl-2-methoxypyridine dihydrochloride

HCID 69331866HCID 69331866, compound

Product 1

HCID 21091009HCID 21091009, compoundYield 41.2%

Procedure

The title compound (1.63 g, 41.2%) was prepared as a powder from 3-(4-methoxymethoxyphenyl)acrylonitrile and 2-methoxy-5-pyridinylhydrazine dihydrochloride in a similar manner to that of Example 14-1.

Sources & evidence

ORD record: ord-f12b364276b44a41a0431ac032621109
Source dataset: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07183306B2

Reaction notes

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