13(S)-Hpode → Linoleic Acid

HRID 351524

Reaction equation

HRID 351524 reaction equation
[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][C@H:6](OO)/[CH:7]=[CH:8]/[CH:9]=[CH:10]\[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=[O:19]>B(O)([O-])[O-].B(O)(O)O.B(O)(O)O.B(O)(O)O.[Na+].[Na+]>[C:18]([OH:20])(=[O:19])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]/[CH:10]=[CH:9]\[CH2:8]/[CH:7]=[CH:6]\[CH2:5][CH2:4][CH2:3][CH2:2][CH3:1]

Participants

3

Reactant 1

HCID 528072013(S)-Hpode

Product 1

HCID 5280450Linoleic Acid

Reagents, catalysts & solvents 1

HCID 86623386Disodium;boric acid;hydrogen borateSolvent

Procedure

13-HPODE, which is a lipid hydroperoxide was produced by the peroxidation of linoleic acid by soybean lipoxygenase-1, in 100 mM di-sodium tetraborate buffer at pH 9.4. After purification by HPLC, the absorption spectrum of 13-HPODE (80 μM) was obtained (FIG. 31). This shows a peak at 234 nm where the conjugated diene absorbs.

Sources & evidence

ORD record
ord-5a4f5e384ffe4cb687776591f97d51e1
Source dataset
uspto-grants-2004_06
Patent number
US06743638B1

Linked notes

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