HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyric Acid → 5-Chloro-2,3-dimethylpentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyric Acid | HCID 6590 | — |
| Reactant | 1,3-Dichloropropane | HCID 8881 | — |
| Reactant | 6-Bromo-2,3-dimethylhexanoic acid | HCID 18942136 | — |
| Product | 5-Chloro-2,3-dimethylpentanoic acid | HCID 18942134 | — |
Reaction Steps
The title compound was prepared as described for 6-bromo-2,3-dimethylhexanoic acid from isobutyric acid (9.67 g, 109.8 mmol), and 1,3-dichloropropane (37.2 g, 329.2 mmol). The product was purified by flash chromatography (CHCl3) to provide the acid (0.9 g, 5%) as a oil, HRMS (M+Li)+ calcd for C7H13O2ClLi 171.0764, found 171.0766.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05830888 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-9dc23f2b8639435eb4cb47e15da30ebc |
| Source note | uspto-grants-1998_11 |