(2S)-3,3-dimethylbutan-2-amine → 3-(2-Hydroxy-6-methylphenylamino)-4-(2,2,1-trimethylpropylamino)-cyclobut-3-ene-1 2-dione

HRID 357298

Reaction equation

HRID 357298 reaction equation
N[C@H](C(C)(C)C)C.[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[C:10]=1[NH:16][C:17]1[C:18](=[O:29])[C:19](=[O:28])[C:20]=1[NH:21][C@H:22]([CH3:27])[C:23]([CH3:26])([CH3:25])[CH3:24]>>[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([CH3:15])[C:10]=1[NH:16][C:17]1[C:18](=[O:29])[C:19](=[O:28])[C:20]=1[NH:21][CH:22]([CH3:27])[C:23]([CH3:24])([CH3:26])[CH3:25]

Participants

3

Reactant 2

HCID 7004913(2S)-3,3-dimethylbutan-2-amineHCID 54402716(R)-3-(2-hydroxy-6-methylphenylamino)-4-(2,2,1-trimethylpropyl-amino)-cyclobut-3-ene-1,2-dione

Product 1

HCID 189374283-(2-Hydroxy-6-methylphenylamino)-4-(2,2,1-trimethylpropylamino)-cyclobut-3-ene-1 2-dione

Procedure

(S)-3-(2-hydroxy-6-methylphenylamino)-4-(2,2,1-trimethylpropylamino)-(cyclobut-3-ene-1,2-dione is produced by the same method by substituting (S)-2-amino-3,3-dimethylbutane for the (R)-2-amino-3,3-dimethylbutane employed in the preceding paragraph.

Sources & evidence

ORD record
ord-9ec4d24d6fb54f2cae3a020b605d96c6
Source dataset
uspto-grants-1998_11
Patent number
US05840764

Linked notes

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