HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 1-(4-(Methylthio)phenyl)ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Thioanisole | HCID 7520 | — |
| Reactant | Carbonyl bromide | HCID 79057 | — |
| Product | 1-(4-(Methylthio)phenyl)ethan-1-one | HCID 74501 | — |
Reaction Steps
The synthesis of bromoketone 2 begins with the Friedel-Crafts reaction between thioanisole and acetyl chloride, to give 4-(methylthio)acetophenone 3 herein referred to as ketosulfide 3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05840924 |
| Source dataset | uspto-grants-1998_11 |
| ORD ID | ord-e4494d6d1d164f64b3a7b30b7bdc8aa6 |
| Source note | uspto-grants-1998_11 |