O-ethylhydroxylamine hydrochloride → 2-[1-(Ethoxyimino)propyl]-3-hydroxy-5-(2,4,6-trimethyl-3-sulfamoylphenyl)cyclohex-2-en-1-one

HRID 35766

Reaction equation

HRID 35766 reaction equation
Cl.[CH2:2]([O:4][NH2:5])[CH3:3].[OH:6][C:7]1[CH2:12][CH:11]([C:13]2[C:18]([CH3:19])=[CH:17][C:16]([CH3:20])=[C:15]([S:21](=[O:24])(=[O:23])[NH2:22])[C:14]=2[CH3:25])[CH2:10][C:9](=[O:26])[C:8]=1[C:27](=O)[CH2:28][CH3:29]>>[CH2:2]([O:4][N:5]=[C:27]([C:8]1[C:9](=[O:26])[CH2:10][CH:11]([C:13]2[C:18]([CH3:19])=[CH:17][C:16]([CH3:20])=[C:15]([S:21](=[O:23])(=[O:24])[NH2:22])[C:14]=2[CH3:25])[CH2:12][C:7]=1[OH:6])[CH2:28][CH3:29])[CH3:3]

Participants

3

Reactant 2

HCID 76850O-ethylhydroxylamine hydrochlorideHCID 178458848HCID 178458848, compound

Product 1

HCID 1360208302-[1-(Ethoxyimino)propyl]-3-hydroxy-5-(2,4,6-trimethyl-3-sulfamoylphenyl)cyclohex-2-en-1-one

Procedure

Reaction of ethoxyamine hydrochloride with 3-hydroxy-5-(2,4,6-trimethyl-3-sulfamoylphenyl)-2-propionylcyclohex-2-en-one following essentially the same procedure as that described in Example 1 part (iv) gave 2-[1-(ethoxyimino)propyl]-3-hydroxy-5-(2,4,6-trimethyl-3-sulfamoylphenyl)cyclohex-2-en-1-one (12). The compound was characterized by its proton magnetic resonance spectrum which is given in Table 5, Example 37.

Sources & evidence

ORD record
ord-b099b8f5a2e24785b4857404ef872c63
Source dataset
uspto-grants-1988_08
Patent number
US04767879

Linked notes

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