2-Butanone, 3-bromo- → 2,3-Dimethyl-8-phenylmethoxyimidazo[1,2-b]pyridazine

HRID 358022

Reaction equation

HRID 358022 reaction equation
[NH2:1][C:2]1[N:3]=[N:4][CH:5]=[CH:6][C:7]=1[O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.Br[CH:17]([CH3:21])[C:18](=O)[CH3:19]>>[CH3:21][C:17]1[N:1]=[C:2]2[C:7]([O:8][CH2:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=3)=[CH:6][CH:5]=[N:4][N:3]2[C:18]=1[CH3:19]

Participants

3

Reactant 2

HCID 131422-Butanone, 3-bromo-HCID 204502733-Amino-4-phenylmethoxypyridazine

Product 1

HCID 204502682,3-Dimethyl-8-phenylmethoxyimidazo[1,2-b]pyridazine

Procedure

Similarly, condensation of the 3-amino-4-phenylmethoxypyridazine with 3-bromo-2-butanone gives the 2,3-dimethyl-8-phenylmethoxyimidazo[1,2-b]pyridazine as shown in the following reaction Scheme IV: ##STR16##

Sources & evidence

ORD record
ord-19852320ec454472b8d80d2ad86ce3af
Source dataset
uspto-grants-1984_08
Patent number
US04464372

Linked notes

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