4-Chlorobenzenesulfonyl chloride → HCID 20066980, compound

HRID 358630

Reaction equation

HRID 358630 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9].[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1>[OH-].[Na+]>[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([S:18]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([OH:10])=[O:9])(=[O:20])=[O:19])=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 73984-Chlorobenzenesulfonyl chlorideHCID 135807-Aminoheptanoic acid

Product 1

HCID 20066980HCID 20066980, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A solution of 7-aminoheptanoic acid in 10% sodium hydroxide solution was treated with 4-chlorobenzenesulphonyl chloride in the manner of Example 1 to give the title compound which, after recrystallisation from aqueous ethanol, had a melting point of 128°-129° C.

Sources & evidence

ORD record
ord-c812be37b9ed44eb8f0793de2ca21202
Source dataset
uspto-grants-1991_03
Patent number
US04997847

Linked notes

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