HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-3-pyruvic acid → HCID 54134943, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-3-pyruvic acid | HCID 803 | — |
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Dimethylazanide | HCID 182180 | — |
| Solvent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Product | HCID 54134943 | HCID 54134943 | — |
Reaction Steps
The same method as described in Example 7 was followed for the preparation of N,N-dimethylamide. 500 mg 3-indolepyruvic acid were reacted with 400 ml HOBt and 570 ml EDC.HCl. 340 microliters of freshly distilled cyclohexylamine and 325 microliters NMM were added to the solution, which was reacted for 5 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05002963 |
| Source dataset | uspto-grants-1991_03 |
| ORD ID | ord-ab4f0216453f46f89472cb195305881f |
| Source note | uspto-grants-1991_03 |