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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 35992Generated: October 23, 2026

Acetic Acid → Dimethyl dicarbonate

https://huagongshe.com/en/reaction/35992

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantCitric AcidHCID 311—
Reactant2,3-Dihydroxybutanedioic AcidHCID 875—
ReactantMaleic AcidHCID 444266—
ProductDimethyl dicarbonateHCID 3086—

Reaction Steps

To each pharmaceutical composition (500 mg) of DMDC 2H2O packed in vials or ampoules in Examples 3 to 8 was added 10 ml of 1 w/v % aqueous lactic acid for dissolution to give injections of DMDC 2H2O. The same procedure was repeated using 3 w/v % aqueous citric acid, 5 w/v % aqueous maleic acid, 6 w/v % aqueous tartaric acid or 10 w/v % aqueous acetic acid to give injections of DMDC 2H2O.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05412089
Source datasetuspto-grants-1995_05
ORD IDord-537b549341e447acb1b62f77ca19c474
Source noteuspto-grants-1995_05