HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-bromobenzoate → 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-bromobenzoate | HCID 12081 | — |
| Reactant | 5-phenyl-2-(2-phenylpropan-2-yl)-2H-tetrazole | HCID 1289594 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester | HCID 11825483 | — |
Reaction Steps
reacting the ortho-transmetalated 2-(1-methyl-1-phenylethyl)-5-phenyl-2H-tetrazole with methyl 4-bromobenzoate in the presence of phosphinated nickel catalyst to give 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05412102 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-42668a80998344b19de3080d89fd669a |
| Source note | uspto-grants-1995_05 |