Methylhydrazine → 3-Amino-1-methyl-5-methylsulfanyl-1H-pyrazole-4-carbonitrile
Reaction equation
CS[C:3](=[C:6]([C:9]#[N:10])[C:7]#[N:8])[S:4][CH3:5].[CH3:11][NH:12][NH2:13]>O>[NH2:8][C:7]1[C:6]([C:9]#[N:10])=[C:3]([S:4][CH3:5])[N:12]([CH3:11])[N:13]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
9.63 g (56.6 mmol) [Bis(methylmercapto)methylene]-malononitrile was suspended in 50 ml water and treated with 3.7 ml (67.9 mmol) methylhydrazine. The mixture was heated at boiling for 1 hour, the reaction solution cooled, the precipitate suction filtered and recrystallised from ethanol.
Workup
- temperatureThe mixture was heated
- temperaturethe reaction solution cooled
- filtrationthe precipitate suction filtered
- customrecrystallised from ethanol
Sources & evidence
- ORD record
- ord-507da0fb6fbf4503b91cb0978cda6a32
- Source dataset
- uspto-grants-1999_02
- Patent number
- US05869686
Reaction notes
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