5-Fluorouridine → HCID 178418321, compound

HRID 3627

Reaction equation

HRID 3627 reaction equation
N([C@@H]1[C@@H](CO)O[C@@H]([N:11]2[CH:19]=[C:17](C)[C:15](=[O:16])[NH:14][C:12]2=O)C1)=[N+]=[N-].F[C@@H]1[C@@H](CO)O[C@@H]([N:28]2C=C(C)C(=O)NC2=O)C1.FC1C(=O)[NH:40][C:41](=O)[N:42](C=1)[C@@H:43]1[O:51][C@H:48]([CH2:49][OH:50])[C@@H:46]([OH:47])[C@H]1O.C1NC2N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C=NC=2C(=S)N=1.OCCCOCN1C=NC2C(=O)NC(N)=NC1=2.C(OCN1C=NC2C(=O)NC(N)=NC1=2)C>>[CH:41]1[N:42]([CH2:43][O:51][CH:48]([CH2:49][OH:50])[CH2:46][OH:47])[C:19]2[N:11]=[C:12]([NH2:28])[N:14]=[C:15]([OH:16])[C:17]=2[N:40]=1

Participants

7

Reactant 6

HCID 94275-FluorouridineHCID 330393'-FluorothymidineHCID 35370ZidovudineHCID 6761666-ThioinosineHCID 1359234559-(3-Hydroxypropoxymethyl)guanineHCID 1360439662-Amino-9-(ethoxymethyl)-1H-purin-6(9H)-one

Product 1

HCID 178418321HCID 178418321, compound

Procedure

3'-deoxy-3'-azidothymidine, 3'-deoxy-3'-fluorothymidine, 5-fluorouridine, 6-mercaptopurine-9-β-D-ribofuranoside, 6-methylmercaptopurine-9-β-D-ribofuranoside, 9-{[(1-hydroxymethyl)ethoxy]-methyl}guanine and 9- (ethoxymethyl)guanine.

Sources & evidence

ORD record
ord-f7b8b5a24c1b45c195681022ace26b53
Source dataset
uspto-grants-1998_03
Patent number
US05734042

Linked notes

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